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Chorioamnionitis

Chorioamnionitis Definition

Chorioamnionitis also known as intra-amniotic infection affects the fetal membranes due to inflammation leading to a bacterial infection. This condition typically results from bacteria ascending from the uterus to the vagina. It usually occurs when labor is prolonged.  

Chorioamnionitis is a complication of pregnancy caused by bacterial infection of the fetal amnion and chorion membranes. 

This condition usually occurs during the second and third trimester, but it can also occur during the first trimester. 

Chorioamnionitis Causes And Risk Factors

The leading causes are E. coli, Group B streptococci, and other anaerobic bacteria.  The main triggering factors of intra-amniotic infection are premature rupture of membrane (PROM).  

This condition can also occur in women who have been exposed to prolonged labor due to the uterus and vagina remain exposed to each other.  

Risk Factors That May Trigger An Infection

  • Low socioeconomic status
  • Preterm labor
  • Having the baby first time
  • Having a baby before the age of 21 years old
  • Many vaginal exams
  • Examining of the uterus and fetus

What Are The Symptoms of Chorioamnionitis?

  • Obscene smelling vaginal discharge
  • Uterine tenderness
  • Sweating
  • Increased fetal heart rate
  • Fever
  • Maternal tachycardia

Chorioamnionitis Diagnosis

During the later stages of pregnancy if you’re experiencing any signs of fever, vaginal discharge, and increased heart rate the doctor might diagnose Chorioamnionitis.  The doctor might also examine your medical history. 

Chorioamnionitis Differential Diagnosis

  • Colitis
  • Round ligament pain
  • Thrombophlebitis
  • Placental abruption
  • Appendicitis
  • Influenza
  • Pneumonia
  • Connective tissue disorders
  • Herpes Simplex Virus Infection

Chorioamnionitis Preventive Measures

If you have bacterial infection making sure to contact your physician

  • Getting examined for group B streptococcus 
  • Make sure to attend your prenatal check-ups

Chorioamnionitis Treatment And Management

The doctor will base any type of treatment depending on the severity of the condition.

Chorioamnionitis Outcome

The doctor determines the outcome base on the severity of the infection and the duration. If you're diagnosed with the condition later in pregnancy, the risk of life threating conditions is less.  

Chorioamnionitis Complications

Maternal Complications

  • Heavy post-partum hemorrhage
  • Premature delivery
  • Pelvic infection
  • Abdominal infection
  • Blood clotting in the pelvis
  • Blood clotting in the lungs
  • Stillbirth
  • Miscarriage

Fetal Or Newborn Complications

  • Bacteremia
  • Pneumonia
  • Respiratory problems
  • Meningitis
  • Intrauterine fetal demise
  • Neonatal sepsis 

Chorioamnionitis Incidence

This condition occurs in around 2% of births in the United States

Chorioamnionitis ICD-9 and ICD-10 Codes

ICD 9 code for chorioamnionitis is 658.4.

ICD-10 code for chorioamnionitis is O41.1 

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